ketapk/frontend/js/app.js

import { MODES, PK_MODELS, CLINICAL_THRESHOLDS, generateSimulationData } from '../../pkCore.js';
import { adjustChartYScale } from './chartManager.js';
import { initCalculatorUI } from './calculator.js';
import { generatePDFReport } from './pdfExport.js';

let currentMode = MODES.ESKETAMINE;
let pkChart = null;

const timelineInputs = Array.from({ length: 61 }, (_, i) => ({
  time: i * 5,
  bolusMg: 0,
  perfRateMgKgH: 0
}));

document.addEventListener('DOMContentLoaded', () => {
  initChart();
  renderTimelineGrid();
  initCalculatorUI(); // Initialise la modale et les événements du calculateur
  setupEventListeners();
  updateSimulation();
});

function initChart() {
  const ctx = document.getElementById('pkChart').getContext('2d');

  pkChart = new Chart(ctx, {
    type: 'line',
    data: {
      labels: timelineInputs.map(d => `${d.time}'`),
      datasets: []
    },
    options: {
      responsive: true,
      maintainAspectRatio: false,
      scales: {
        y: {
          beginAtZero: true,
          max: CLINICAL_THRESHOLDS[currentMode].maxScale,
          title: { display: true, text: 'Cp (ng/mL)', color: '#94a3b8' },
          grid: { color: 'rgba(51, 65, 85, 0.4)' }
        },
        x: {
          title: { display: true, text: 'Temps (minutes)', color: '#94a3b8' },
          grid: { color: 'rgba(51, 65, 85, 0.4)' }
        }
      },
      plugins: {
        legend: { labels: { color: '#f8fafc' } },
        annotation: { annotations: {} }
      }
    }
  });
}

function updateSimulation() {
  const weight = parseFloat(document.getElementById('inputWeight').value) || 70;
  const datasets = [];

  if (document.getElementById('chkDomino').checked) {
    datasets.push({
      label: PK_MODELS.DOMINO.name,
      data: generateSimulationData({ model: PK_MODELS.DOMINO, weightKg: weight, timelineInputs }),
      borderColor: PK_MODELS.DOMINO.color,
      borderWidth: 3,
      tension: 0.2
    });
  }

  if (document.getElementById('chkClements').checked) {
    datasets.push({
      label: PK_MODELS.CLEMENTS.name,
      data: generateSimulationData({ model: PK_MODELS.CLEMENTS, weightKg: weight, timelineInputs }),
      borderColor: PK_MODELS.CLEMENTS.color,
      borderWidth: 3,
      tension: 0.2
    });
  }

  if (document.getElementById('chkKamp').checked) {
    datasets.push({
      label: PK_MODELS.KAMP.name,
      data: generateSimulationData({ model: PK_MODELS.KAMP, weightKg: weight, timelineInputs }),
      borderColor: PK_MODELS.KAMP.color,
      borderWidth: 3,
      tension: 0.2
    });
  }

  pkChart.data.datasets = datasets;
  
  // Ajustement dynamique de l'échelle Y à 110 % si besoin
  adjustChartYScale(pkChart, currentMode, datasets);
  
  pkChart.update();
}

function renderTimelineGrid() {
  const container = document.getElementById('timelineGrid');
  container.innerHTML = '';

  timelineInputs.forEach((item, idx) => {
    const col = document.createElement('div');
    col.className = 'flex-1 bg-slate-900 border border-slate-700/60 rounded-xl p-2 text-center text-xs flex flex-col gap-1.5 min-w-[85px]';
    col.innerHTML = `
      <div class="font-bold text-amber-400 border-b border-slate-800 pb-1">${item.time} min</div>
      <div>
        <span class="text-[10px] text-slate-400 block mb-0.5">Bolus (mg)</span>
        <input type="number" data-idx="${idx}" data-field="bolusMg" value="${item.bolusMg || ''}" placeholder="0" class="w-full bg-slate-800 border border-slate-700 text-center rounded text-white py-1 outline-none focus:border-amber-500">
      </div>
      <div>
        <span class="text-[10px] text-slate-400 block mb-0.5">Perf (mg/kg/h)</span>
        <input type="number" data-idx="${idx}" data-field="perfRateMgKgH" value="${item.perfRateMgKgH || ''}" placeholder="0" class="w-full bg-slate-800 border border-slate-700 text-center rounded text-white py-1 outline-none focus:border-amber-500">
      </div>
    `;
    container.appendChild(col);
  });
}

function setupEventListeners() {
  document.getElementById('timelineGrid').addEventListener('input', (e) => {
    const idx = e.target.dataset.idx;
    const field = e.target.dataset.field;
    if (idx !== undefined && field) {
      timelineInputs[idx][field] = parseFloat(e.target.value) || 0;
      updateSimulation();
    }
  });

  document.getElementById('btnEsk').addEventListener('click', () => setMode(MODES.ESKETAMINE));
  document.getElementById('btnRac').addEventListener('click', () => setMode(MODES.RACEMIQUE));

  ['inputWeight', 'chkDomino', 'chkClements', 'chkKamp'].forEach(id => {
    document.getElementById(id).addEventListener('change', updateSimulation);
  });

  document.getElementById('btnRaz').addEventListener('click', () => {
    timelineInputs.forEach(item => { item.bolusMg = 0; item.perfRateMgKgH = 0; });
    renderTimelineGrid();
    updateSimulation();
  });

  document.getElementById('btnExportPdf').addEventListener('click', () => {
    const patientData = {
      weight: document.getElementById('inputWeight').value || 70,
      age: document.getElementById('inputAge').value || 50,
      height: document.getElementById('inputHeight').value || 170
    };
    generatePDFReport(pkChart, patientData, currentMode);
  });
}

function setMode(mode) {
  currentMode = mode;
  const btnEsk = document.getElementById('btnEsk');
  const btnRac = document.getElementById('btnRac');
  const concInput = document.getElementById('inputConc');

  if (mode === MODES.ESKETAMINE) {
    btnEsk.className = 'px-4 py-1.5 rounded-lg text-xs font-bold bg-amber-500 text-slate-950 shadow-md shadow-amber-500/30';
    btnRac.className = 'px-4 py-1.5 rounded-lg text-xs font-bold text-slate-400 hover:text-slate-200';
    concInput.value = CLINICAL_THRESHOLDS[MODES.ESKETAMINE].defaultConcentration;
  } else {
    btnRac.className = 'px-4 py-1.5 rounded-lg text-xs font-bold bg-fuchsia-500 text-slate-950 shadow-md shadow-fuchsia-500/30';
    btnEsk.className = 'px-4 py-1.5 rounded-lg text-xs font-bold text-slate-400 hover:text-slate-200';
    concInput.value = CLINICAL_THRESHOLDS[MODES.RACEMIQUE].defaultConcentration;
  }
  updateSimulation();
}